Terms of Use

Welcome to the Takeda website for the Joint Health Initiative (the “Website”). The information
provided on this Website is about Takeda and its products. It is for general information and
education purposes only. Please read and review these Terms of Use carefully before accessing and
using this Website.

1. Use of Takeda Website

Your access to and use of this Website is subject to the following terms and conditions and all
applicable laws. By using any of the contents of this Website, including but not limited to, all
text and images (the “Contents”) you hereby acknowledge that you have read, understood and agreed,
without limitation or qualification, to these Terms of Use and acknowledge that any other
agreements between you and Takeda Development Center Americas, Inc, having its offices at 95 Hayden
Ave, Lexington, MA, USA (“Takeda”) are superseded with respect to this subject matter.

2. Information purposes

This Website may contain specific information relating to various Takeda medicines, including but
not limited to, prescription only medicines. All information presented on this Website is solely
intended for Healthcare Professionals only. For the avoidance of doubt, a “Healthcare Professional”
refers to any natural person that is a member of the medical, dental, pharmacy or nursing
profession or any other person, who in the course of his/her professional activities may prescribe,
purchase, supply, recommend or administer a medicine or medical devices. By using this Website you
certify that you have a license to operate as a Healthcare Professional in the country this Site is
accessible from. This section of the Website is not intended for patients’ access and in this
regard, patients must not act upon this Website.

All information presented on this Website is solely intended for educational and informational
purposes only. Please note that approved prescribing information must guide the appropriate use of
all medicines and before prescribing any medicine, Healthcare Professionals should
consult the approved prescribing information for that medicine in their country.

This Website may contain information about products that may not be available in all countries, or
may be available under different trademarks, for different indications, in different dosages, or
in different strengths and subject to different regulatory requirements depending on the
country of use. Many of the products listed are available only by prescription through
Healthcare professionals. Nothing contained herein should be considered a solicitation,
promotion or indication for any prescription drug including the ones under development.

All information and references relating to handling, storage or use of products, to be implied from
the relevant resource, are based on Takeda's knowledge at the time such recommendations are made.

The information provided on this Website does not constitute an offer of or solicitation for the
purchase or disposal of, trading or any transaction in any Takeda securities, its affiliates and/or
partners securities. Investors must not rely on this information for investment decisions.

3. Use of Contents and Intellectual Property Rights

The entire Contents of this Website is subject to the relevant trademark and copyright
protection. The trademarks, logos and service marks (collectively, the "Trademarks") used or
mentioned on this site are registered and unregistered trademarks of Takeda, one of its affiliates
and are protected by applicable law. You may download, display or print information from this
Website solely for non-commercial personal use or for use in non-commercial education and
scientific work. No modification for further reproduction of the content is permitted and all
copyright and other proprietary notices contained herein shall be retained in all copies. The
content may otherwise not be copied or used in any way without the prior written consent of Takeda
or except as provided in these Terms of Use. This Website and all of its Contents, are owned by
Takeda, its affiliates and/or partners.

No license to or right in the Contents or any trademarks, patents, designs, trade
secrets, technologies, products, process and other proprietary rights of Takeda, its
affiliates and/or partners is granted to or conferred upon you.

4. Information “as is”

Takeda will use reasonable efforts to include accurate and up-to-date information on
this Website but makes no warranties or representations of any kind as to its accuracy
or completeness. Takeda disclaims all warranties, expressed or implied, including warranties of
merchantability or fitness for a particular purpose. Furthermore, Takeda neither warrants nor
represents that your use of any of the Contents on this Website will not infringe rights of third
parties, not owned by Takeda or any of its affiliates. You agree that access to and use of this
Website and the Contents thereof is at your own risk.

5. Disclaimed liability

Neither Takeda nor any party involved in creating, producing or delivering this Website shall be
liable for any damages or injury, including without limitation, direct, indirect, incidental,
consequential, punitive, and special or other damages, lost opportunities, lost profit or any loss
or damages of any kind arising out of access to, use of or inability to use this Website, or any
errors or omissions in the Contents thereof. This limitation includes damages to, or for any
viruses that may affect your computer equipment.

6. Data Privacy

Takeda respects the privacy of its Website users. Please refer to Takeda’s Privacy Notice that
explains user’s rights and responsibilities with respect to information that is disclosed on this
Website.

7. Links to other internet sites

This Website may contain links or references to other internet sites maintained by third parties
over which Takeda has no control. Such links are provided merely as a convenience. Similarly, this
Website may be accessed from third party links over which Takeda has no control. Takeda makes no
warranties or representations of any kind as to the truthfulness, accuracy, currency, completeness
of any information contained or compliance with applicable law in such third- party internet sites
and assumes no liability for any damages or injuries of any kind arising from such content or
information. Inclusion of any third-party links does not imply any endorsement or recommendation by
Takeda.

8. Use of Questions and Comments

Except for transmissions covered by our Privacy Statement or made by
Healthcare Professionals pursuant to the applicable laws, EU Regulations and Codes,
communications which you forward to this Website or otherwise to Takeda shall be deemed
non-confidential and non-proprietary and Takeda shall not be required to respond. Subject to the
applicable laws, Takeda and its affiliates reserve the right to use such communications for any
purpose and to reproduce, publish and disclose this information to third parties without
limitation or compensation. Takeda and its affiliates also are free to use without
limitation and without compensation to you any ideas, concepts, know-how, techniques or the like
contained in any communication you send to Takeda for any purpose, including, but not limited to,
developing, manufacturing and marketing products.

9. Applicable law and place of jurisdiction

Any breaches of the terms and conditions in the Terms of Use, Takeda reserves the right, to take
corrective action, including, but not limited to, preventing you from using the services offered by
Takeda and removing any information, data and content communicated to this site, at any moment and
without notice.

These Terms of Use, the Contents of this Website and your use of it shall be governed by and
construed in accordance with substantive laws of the United States of America. Any conflict arising
out or in relation hereto, if not solved amicably, shall be settled by courts of competent
jurisdiction in the state of Massachusetts, USA.

In case any part of these Terms of Use be held invalid, illegal or unenforceable, the validity,
legality and enforceability of the remaining provisions shall not in any way be
affected or impaired.

10. Update of the Terms of Use and other policies provided on this Takeda Website

Takeda reserves the right to alter or delete material from the Website at any time, and Takeda may,
at any time, revise these Terms of Use and/or any other policies set forth in this Website by
updating this posting. You are bound by any such revisions and should, therefore,
periodically visit this page to review the then current Terms of Use and policies.

Dated: 24 September 2021

Imprint:

The copyright and ownership of this Website reside with:

Takeda Development Center Americas, Inc.
95 Hayden Ave Lexington, MA 02421
USA

Page Footer:

jointhealthinitiative.com has been developed by Takeda Development Center Americas, Inc. as an
educational resource for healthcare providers (and patients).

Last edited 16 September 2021